MP Board · Class 12 · Biology · Principles of Inheritance and VariationWhat type of mutation is responsible for sickle-cell anaemia?
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Total Attempts: 5
Accuracy Rate: 60%
Step-by-Step Solution
Sickle-cell anaemia is caused by a point mutation where glutamic acid is replaced by valine in the beta-globin chain.
Detailed Options Breakdown
Option : Frameshift mutation
Incorrect choice. This distractor represents a common misunderstanding of the core principles of Principles of Inheritance and Variation.
Option 1: Point mutation (Correct Answer)
Correct choice. Refer to the step-by-step verified solution guidelines above for details.
Option 2: Chromosomal deletion
Incorrect choice. This distractor represents a common misunderstanding of the core principles of Principles of Inheritance and Variation.
Option 3: Polyploidy
Incorrect choice. This distractor represents a common misunderstanding of the core principles of Principles of Inheritance and Variation.
💡 Study Guide: This question tests core syllabus concepts from Principles of Inheritance and Variation. For formulas, key summaries, and mock exam reference guides, read the full Principles of Inheritance and Variation Revision Notes.